The Research Behind Our Protocol

The Research Behind Our Protocol

Every claim we make about supplements, equipment, and protocols is backed by published research. Here are the studies that shape our editorial positioning.

Why we publish our sources

Longevity is dominated by influencer claims with little research grounding. Our editorial standard: every protocol recommendation cites the research that supports it. If we make a claim we can't back, we don't make it.

Sauna & Heat Therapy Research

Laukkanen et al. 2018 — Sauna and All-Cause Mortality

Mayo Clinic Proceedings · 23-year follow-up on 2,300+ Finnish men · The foundational research showing 24-40% reduction in all-cause mortality with frequent sauna use.

Our coverage: Sauna Dose-Response Curve · Complete Infrared Sauna Guide

Patrick & Johnson 2020 — Heat Shock Proteins and Cellular Adaptation

Experimental Gerontology · Review of HSP70 cellular response to heat stress. Foundation for understanding cardiovascular conditioning via sauna.

NMN & NAD+ Research

Yoshino et al. 2021 — Long-term NMN Supplementation Human Trial

Science · Foundational human trial demonstrating NAD+ elevation with sustained NMN supplementation at 250mg/day. Established the dose-response framework.

Our coverage: NMN Dose Threshold · Complete NMN Guide

Sinclair Lab — Multi-year publications on NMN and cellular aging

Series of mouse studies establishing NMN cellular mechanism and aging implications. Foundation for the threshold dose framework most longevity practitioners use.

Cold Exposure Research

Söberg et al. 2021 — Cold Exposure and Brown Adipose Tissue

Cell Reports Medicine · Established mechanism for cold exposure activating BAT and improving metabolic flexibility in healthy adults.

Our coverage: Cold Plunge for Brain Fog · Complete Cold Plunge Guide

Huberman Lab podcast/research syntheses

Andrew Huberman's research syntheses on cold exposure protocols, vagal tone, and norepinephrine effects. Authoritative protocols backed by mechanism research.

Red Light Therapy Research

Hamblin 2017 — Photobiomodulation Mechanisms

Photonics · Comprehensive review of red and near-infrared light cellular effects. Foundation for the 100 mW/cm² irradiance threshold framework.

Our coverage: Red Light Irradiance Threshold · Best Red Light Panel 2026

Collagen & Glycine Research

Choi et al. 2019 — Marine Collagen Bioavailability

Marine Drugs · Comparative study of marine vs bovine collagen absorption and amino acid profile. Established the bioavailability advantage of marine sources.

Our coverage: Marine vs Bovine Collagen · Best Marine Collagen 2026

Editorial Standards

Every product recommendation we make follows this framework:

  1. Research-grounded claim. The protocol or product is supported by published research.
  2. Threshold-dose verification. Where dose matters, we recommend at threshold dose, not below.
  3. Affiliate disclosure. Where affiliate relationships exist, they're disclosed at point of recommendation per FTC guidelines.
  4. "Where it loses points" honesty. Every product recommendation includes the genuine downsides, not just marketing.
  5. Independent editorial. Commission rates don't determine product rankings. We applied to every affiliate program after selecting products editorially.

Start with the foundation

The protocols we recommend compound on top of supplement foundation. The Starter Stack is the entry point.

See the Longevity Starter Stack — $99 →